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A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis

Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder characterized by recurrent eczematous lesions. Interleukin (IL)−33, a cytokine of the IL-1 family, was found to play an important role in the pathogenesis of AD. As a key component of the inflammasome, NLRP3 has been most...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Yao, Lu, Zhou, Yijing, Gu, Xiaoqun, Wang, Can, Bao, Kaifan, Sun, Yang, Hong, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463682/
https://www.ncbi.nlm.nih.gov/pubmed/34561424
http://dx.doi.org/10.1038/s41419-021-04159-9