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Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer

Adipocytes influence breast cancer behaviour via fatty acid release into the tumour microenvironment. Co-culturing human adipocytes and breast cancer cells increased CD36 expression, with fatty acid import into breast cancer cells. Genetic ablation of CD36 attenuates adipocyte-induced epithelial-mes...

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Detalles Bibliográficos
Autores principales: Gyamfi, Jones, Yeo, Joo Hye, Kwon, Doru, Min, Byung Soh, Cha, Yoon Jin, Koo, Ja Seung, Jeong, Joon, Lee, Jinu, Choi, Junjeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463699/
https://www.ncbi.nlm.nih.gov/pubmed/34561446
http://dx.doi.org/10.1038/s41523-021-00324-7