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Scaling of joint mass and metabolism fluctuations in in silico cell-laden spheroids

Variations and fluctuations are characteristic features of biological systems and are also manifested in cell cultures. Here, we describe a computational pipeline for identifying the range of three-dimensional (3D) cell-aggregate sizes in which nonisometric scaling emerges in the presence of joint m...

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Detalles Bibliográficos
Autores principales: Botte, Ermes, Biagini, Francesco, Magliaro, Chiara, Rinaldo, Andrea, Maritan, Amos, Ahluwalia, Arti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463845/
https://www.ncbi.nlm.nih.gov/pubmed/34526399
http://dx.doi.org/10.1073/pnas.2025211118