Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis

In plasma, iron is normally bound to transferrin, the principal protein in blood responsible for binding and transporting iron throughout the body. However, in conditions of iron overload when the iron-binding capacity of transferrin is exceeded, non–transferrin-bound iron (NTBI) appears in plasma....

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Detalles Bibliográficos
Autores principales: Fisher, Allison L., Srole, Daniel N., Palaskas, Nicolaos J., Meriwether, David, Reddy, Srinivasa T., Ganz, Tomas, Nemeth, Elizabeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463868/
https://www.ncbi.nlm.nih.gov/pubmed/34480898
http://dx.doi.org/10.1016/j.jbc.2021.101156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463868/
https://www.ncbi.nlm.nih.gov/pubmed/34480898
http://dx.doi.org/10.1016/j.jbc.2021.101156

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