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Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis
In plasma, iron is normally bound to transferrin, the principal protein in blood responsible for binding and transporting iron throughout the body. However, in conditions of iron overload when the iron-binding capacity of transferrin is exceeded, non–transferrin-bound iron (NTBI) appears in plasma....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463868/ https://www.ncbi.nlm.nih.gov/pubmed/34480898 http://dx.doi.org/10.1016/j.jbc.2021.101156 |