Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P

Lack of simple and robust methods to determine complement activation in human serum induced by antigen–antibody complexes is a major hurdle for monitoring therapeutic antibody drug quality and stability. Dezamizumab is a humanized IgG1 monoclonal antibody that binds to serum amyloid P component (SAP...

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Detalles Bibliográficos
Autores principales: Ma, Jianhong, Liu, Qi, White, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463879/
https://www.ncbi.nlm.nih.gov/pubmed/34461096
http://dx.doi.org/10.1016/j.jbc.2021.101136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463879/
https://www.ncbi.nlm.nih.gov/pubmed/34461096
http://dx.doi.org/10.1016/j.jbc.2021.101136

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