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Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P
Lack of simple and robust methods to determine complement activation in human serum induced by antigen–antibody complexes is a major hurdle for monitoring therapeutic antibody drug quality and stability. Dezamizumab is a humanized IgG1 monoclonal antibody that binds to serum amyloid P component (SAP...
Autores principales: | Ma, Jianhong, Liu, Qi, White, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463879/ https://www.ncbi.nlm.nih.gov/pubmed/34461096 http://dx.doi.org/10.1016/j.jbc.2021.101136 |
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