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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation

INTRODUCTION: Arctigenin, derived from Arctium lappa L., has multiple pharmacological activities, including immunoregulatory, anti-diabetic, anti-tumor, and neuroprotective effects. Nevertheless, the potential therapeutic target of arctigenin in modulating inflammation remains undefined. OBJECTIVES:...

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Detalles Bibliográficos
Autores principales: Li, Heng, Zhang, Xianglei, Xiang, Caigui, Feng, Chunlan, Fan, Chen, Liu, Moting, Lu, Huimin, Su, Haixia, Zhou, Yu, Qi, Qing, Xu, Yechun, Tang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463927/
https://www.ncbi.nlm.nih.gov/pubmed/34603793
http://dx.doi.org/10.1016/j.jare.2021.02.006