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Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction

Rapidly evolving RNA viruses continuously produce minority haplotypes that can become dominant if they are drug-resistant or can better evade the immune system. Therefore, early detection and identification of minority viral haplotypes may help to promptly adjust the patient’s treatment plan prevent...

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Detalles Bibliográficos
Autores principales: Knyazev, Sergey, Tsyvina, Viachaslau, Shankar, Anupama, Melnyk, Andrew, Artyomenko, Alexander, Malygina, Tatiana, Porozov, Yuri B, Campbell, Ellsworth M, Switzer, William M, Skums, Pavel, Mangul, Serghei, Zelikovsky, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464054/
https://www.ncbi.nlm.nih.gov/pubmed/34214168
http://dx.doi.org/10.1093/nar/gkab576