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Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction
Rapidly evolving RNA viruses continuously produce minority haplotypes that can become dominant if they are drug-resistant or can better evade the immune system. Therefore, early detection and identification of minority viral haplotypes may help to promptly adjust the patient’s treatment plan prevent...
Autores principales: | Knyazev, Sergey, Tsyvina, Viachaslau, Shankar, Anupama, Melnyk, Andrew, Artyomenko, Alexander, Malygina, Tatiana, Porozov, Yuri B, Campbell, Ellsworth M, Switzer, William M, Skums, Pavel, Mangul, Serghei, Zelikovsky, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464054/ https://www.ncbi.nlm.nih.gov/pubmed/34214168 http://dx.doi.org/10.1093/nar/gkab576 |
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