Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration

Cell engineering is commonly limited to the serial manipulation of a single gene or locus. The recently discovered CRISPR-associated transposases (CASTs) could manipulate multiple sets of genes to achieve predetermined cell diversity, with orthogonal CASTs being able to manipulate them in parallel....

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Detalles Bibliográficos
Autores principales: Yang, Siqi, Zhang, Yiwen, Xu, Jiaqi, Zhang, Jiao, Zhang, Jieze, Yang, Junjie, Jiang, Yu, Yang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464060/
https://www.ncbi.nlm.nih.gov/pubmed/34478496
http://dx.doi.org/10.1093/nar/gkab752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464060/
https://www.ncbi.nlm.nih.gov/pubmed/34478496
http://dx.doi.org/10.1093/nar/gkab752

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