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Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer–target gene regulatory interactions
A growing amount of evidence in literature suggests that germline sequence variants and somatic mutations in non-coding distal regulatory elements may be crucial for defining disease risk and prognostic stratification of patients, in genetic disorders as well as in cancer. Their functional interpret...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464068/ https://www.ncbi.nlm.nih.gov/pubmed/34197622 http://dx.doi.org/10.1093/nar/gkab547 |