XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase

Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected seDSB ends is crucial for HR. The coordinated actions of MRE11-CtIP nuclease...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Abhishek Bharadwaj, Erasimus, Hélène, Pinto, Lia, Caron, Marie-Christine, Gopaul, Diyavarshini, Peterlini, Thibaut, Neumann, Katrin, Nazarov, Petr V, Fritah, Sabrina, Klink, Barbara, Herold-Mende, Christel C, Niclou, Simone P, Pasero, Philippe, Calsou, Patrick, Masson, Jean-Yves, Britton, Sébastien, Van Dyck, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464071/
https://www.ncbi.nlm.nih.gov/pubmed/34500463
http://dx.doi.org/10.1093/nar/gkab785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464071/
https://www.ncbi.nlm.nih.gov/pubmed/34500463
http://dx.doi.org/10.1093/nar/gkab785

Ejemplares similares