YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

In the absence of the scanning ribosomes that unwind mRNA coding sequences and 5′UTRs, mRNAs are likely to form secondary structures and intermolecular bridges. Intermolecular base pairing of non polysomal mRNAs is involved in stress granule (SG) assembly when the pool of mRNAs freed from ribosomes...

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Detalles Bibliográficos
Autores principales: Budkina, Karina, El Hage, Krystel, Clément, Marie-Jeanne, Desforges, Bénédicte, Bouhss, Ahmed, Joshi, Vandana, Maucuer, Alexandre, Hamon, Loic, Ovchinnikov, Lev P, Lyabin, Dmitry N, Pastré, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464072/
https://www.ncbi.nlm.nih.gov/pubmed/34469566
http://dx.doi.org/10.1093/nar/gkab748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464072/
https://www.ncbi.nlm.nih.gov/pubmed/34469566
http://dx.doi.org/10.1093/nar/gkab748

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