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YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells
In the absence of the scanning ribosomes that unwind mRNA coding sequences and 5′UTRs, mRNAs are likely to form secondary structures and intermolecular bridges. Intermolecular base pairing of non polysomal mRNAs is involved in stress granule (SG) assembly when the pool of mRNAs freed from ribosomes...
Autores principales: | Budkina, Karina, El Hage, Krystel, Clément, Marie-Jeanne, Desforges, Bénédicte, Bouhss, Ahmed, Joshi, Vandana, Maucuer, Alexandre, Hamon, Loic, Ovchinnikov, Lev P, Lyabin, Dmitry N, Pastré, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464072/ https://www.ncbi.nlm.nih.gov/pubmed/34469566 http://dx.doi.org/10.1093/nar/gkab748 |
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