Structural recognition of the mRNA 3′ UTR by PUF-8 restricts the lifespan of C. elegans

The molecular mechanisms of aging are unsolved fundamental biological questions. Caenorhabditis elegans is an ideal model organism for investigating aging. PUF-8, a PUF (Pumilio and FBF) protein in C. elegans, is crucial for germline development through binding with the 3′ untranslated regions (3′ U...

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Detalles Bibliográficos
Autores principales: Xu, Zheng, Zhao, Jie, Hong, Minjie, Zeng, Chenming, Guang, Shouhong, Shi, Yunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464079/
https://www.ncbi.nlm.nih.gov/pubmed/34478557
http://dx.doi.org/10.1093/nar/gkab754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464079/
https://www.ncbi.nlm.nih.gov/pubmed/34478557
http://dx.doi.org/10.1093/nar/gkab754

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