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Structural recognition of the mRNA 3′ UTR by PUF-8 restricts the lifespan of C. elegans

The molecular mechanisms of aging are unsolved fundamental biological questions. Caenorhabditis elegans is an ideal model organism for investigating aging. PUF-8, a PUF (Pumilio and FBF) protein in C. elegans, is crucial for germline development through binding with the 3′ untranslated regions (3′ U...

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Detalles Bibliográficos
Autores principales:	Xu, Zheng, Zhao, Jie, Hong, Minjie, Zeng, Chenming, Guang, Shouhong, Shi, Yunyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464079/ https://www.ncbi.nlm.nih.gov/pubmed/34478557 http://dx.doi.org/10.1093/nar/gkab754

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