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MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling
BACKGROUND: Cell invasion is a hallmark of metastatic cancer, leading to unfavorable clinical outcomes. In this study, we established two highly invasive lung cancer cell models (A549-i8 and H1299-i8) and identified mesoderm-specific transcript (MEST) as a novel invasive regulator of lung cancer. We...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464132/ https://www.ncbi.nlm.nih.gov/pubmed/34560900 http://dx.doi.org/10.1186/s13046-021-02107-1 |