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MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling

BACKGROUND: Cell invasion is a hallmark of metastatic cancer, leading to unfavorable clinical outcomes. In this study, we established two highly invasive lung cancer cell models (A549-i8 and H1299-i8) and identified mesoderm-specific transcript (MEST) as a novel invasive regulator of lung cancer. We...

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Detalles Bibliográficos
Autores principales:	Wang, Yang, Zhang, Jing, Li, Yang-Jia, Yu, Nan-Nan, Liu, Wan-Ting, Liang, Jun-Ze, Xu, Wen Wen, Sun, Zheng-Hua, Li, Bin, He, Qing-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464132/ https://www.ncbi.nlm.nih.gov/pubmed/34560900 http://dx.doi.org/10.1186/s13046-021-02107-1

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