Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia

BACKGROUND: Relapsed acute myeloid leukemia (AML) is associated with the acquisition of additional somatic mutations which are thought to drive phenotypic adaptability, clonal selection and evolution of leukemic clones during treatment. We performed high throughput exome sequencing of matched presen...

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Detalles Bibliográficos
Autores principales: Mat Yusoff, Yuslina, Ahid, Fadly, Abu Seman, Zahidah, Abdullah, Julia, Kamaluddin, Nor Rizan, Esa, Ezalia, Zakaria, Zubaidah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464159/
https://www.ncbi.nlm.nih.gov/pubmed/34560908
http://dx.doi.org/10.1186/s13039-021-00561-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464159/
https://www.ncbi.nlm.nih.gov/pubmed/34560908
http://dx.doi.org/10.1186/s13039-021-00561-2

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