Pharmacokinetics of zonisamide after oral single dosing and multiple‐dose escalation administration in domestic chickens (Gallus gallus)

BACKGROUND: There are few effective drugs for treatment of seizures in avian species. OBJECTIVES: To investigate the pharmacokinetics and safety of zonisamide in chickens. METHODS: Phase 1: chickens (n = 4) received a single oral dose of zonisamide at 20 mg/kg. Blood samples were collected intermitt...

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Detalles Bibliográficos
Autores principales: de Matos, Ricardo, Noonan, Brendan P., Schaefer, Deanna M.W., Morrisey, James, Dewey, Curtis, Buckles, Elizabeth L., Boothe, Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464239/
https://www.ncbi.nlm.nih.gov/pubmed/34004072
http://dx.doi.org/10.1002/vms3.512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464239/
https://www.ncbi.nlm.nih.gov/pubmed/34004072
http://dx.doi.org/10.1002/vms3.512

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