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PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice

Renal fibrosis is characterized by glomerulosclerosis and tubulointerstitial fibrosis in diabetic nephropathy (DN). We aimed to evaluate the effects of PP2 on renal fibrosis of DN. GSE33744 and GSE86300 were downloaded from the GEO database. Firstly, 839 DEGs were identified between nondiabetic and...

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Detalles Bibliográficos
Autores principales: Wei, Jinying, Deng, Xinna, Li, Yang, Li, Runmei, Yang, Zhaohua, Li, Xiuyuan, Song, Shan, Shi, Yonghong, Duan, Huijun, Wu, Haijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464423/
https://www.ncbi.nlm.nih.gov/pubmed/34580604
http://dx.doi.org/10.1155/2021/7394344