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CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape, compromising the effectiveness of existing vaccines and neutralizing antibodies. An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a strategy against SARS-CoV-2 variants. Here, we id...

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Detalles Bibliográficos
Autores principales: Geng, Jiejie, Chen, Liang, Yuan, Yufeng, Wang, Ke, Wang, Youchun, Qin, Chuan, Wu, Guizhen, Chen, Ruo, Zhang, Zheng, Wei, Ding, Du, Peng, Zhang, Jun, Lin, Peng, Zhang, Kui, Deng, Yongqiang, Xu, Ke, Liu, Jiangning, Sun, Xiuxuan, Guo, Ting, Yang, Xu, Wu, Jiao, Jiang, Jianli, Li, Ling, Zhang, Kun, Wang, Zhe, Zhang, Jing, Yan, Qingguo, Zhu, Hua, Zheng, Zhaohui, Miao, Jinlin, Fu, Xianghui, Yang, Fengfan, Chen, Xiaochun, Tang, Hao, Zhang, Yang, Shi, Ying, Zhu, Yumeng, Pei, Zhuo, Huo, Fei, Liang, Xue, Wang, Yatao, Wang, Qingyi, Xie, Wen, Li, Yirong, Shi, Mingyan, Bian, Huijie, Zhu, Ping, Chen, Zhi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464593/
https://www.ncbi.nlm.nih.gov/pubmed/34564690
http://dx.doi.org/10.1038/s41392-021-00760-8