Adult brain neurons require continual expression of the schizophrenia-risk gene Tcf4 for structural and functional integrity

The schizophrenia-risk gene Tcf4 has been widely studied in the context of brain development using mouse models of haploinsufficiency, in utero knockdown and embryonic deletion. However, Tcf4 continues to be abundantly expressed in adult brain neurons where its functions remain unknown. Given the im...

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Detalles Bibliográficos
Autores principales: Sarkar, Dipannita, Shariq, Mohammad, Dwivedi, Deepanjali, Krishnan, Nirmal, Naumann, Ronald, Bhalla, Upinder Singh, Ghosh, Hiyaa Singhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464606/
https://www.ncbi.nlm.nih.gov/pubmed/34564703
http://dx.doi.org/10.1038/s41398-021-01618-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464606/
https://www.ncbi.nlm.nih.gov/pubmed/34564703
http://dx.doi.org/10.1038/s41398-021-01618-x

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