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Adult brain neurons require continual expression of the schizophrenia-risk gene Tcf4 for structural and functional integrity
The schizophrenia-risk gene Tcf4 has been widely studied in the context of brain development using mouse models of haploinsufficiency, in utero knockdown and embryonic deletion. However, Tcf4 continues to be abundantly expressed in adult brain neurons where its functions remain unknown. Given the im...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464606/ https://www.ncbi.nlm.nih.gov/pubmed/34564703 http://dx.doi.org/10.1038/s41398-021-01618-x |