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Activation of the dorsal, but not the ventral, hippocampus relieves neuropathic pain in rodents

Accumulating evidence suggests hippocampal impairment under the chronic pain phenotype. However, it is unknown whether neuropathic behaviors are related to dysfunction of the hippocampal circuitry. Here, we enhanced hippocampal activity by pharmacological, optogenetic, and chemogenetic techniques to...

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Detalles Bibliográficos
Autores principales: Wei, Xuhong, Centeno, Maria Virginia, Ren, Wenjie, Borruto, Anna Maria, Procissi, Daniele, Xu, Ting, Jabakhanji, Rami, Mao, Zuchao, Kim, Haram, Li, Yajing, Yang, Yiyuan, Gutruf, Philipp, Rogers, John A., Surmeier, D. James, Radulovic, Jelena, Liu, Xianguo, Martina, Marco, Apkarian, Apkar Vania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464622/
https://www.ncbi.nlm.nih.gov/pubmed/34160168
http://dx.doi.org/10.1097/j.pain.0000000000002279