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Activation of the dorsal, but not the ventral, hippocampus relieves neuropathic pain in rodents
Accumulating evidence suggests hippocampal impairment under the chronic pain phenotype. However, it is unknown whether neuropathic behaviors are related to dysfunction of the hippocampal circuitry. Here, we enhanced hippocampal activity by pharmacological, optogenetic, and chemogenetic techniques to...
Autores principales: | Wei, Xuhong, Centeno, Maria Virginia, Ren, Wenjie, Borruto, Anna Maria, Procissi, Daniele, Xu, Ting, Jabakhanji, Rami, Mao, Zuchao, Kim, Haram, Li, Yajing, Yang, Yiyuan, Gutruf, Philipp, Rogers, John A., Surmeier, D. James, Radulovic, Jelena, Liu, Xianguo, Martina, Marco, Apkarian, Apkar Vania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464622/ https://www.ncbi.nlm.nih.gov/pubmed/34160168 http://dx.doi.org/10.1097/j.pain.0000000000002279 |
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