Alisporivir Improves Mitochondrial Function in Skeletal Muscle of mdx Mice but Suppresses Mitochondrial Dynamics and Biogenesis

Mitigation of calcium-dependent destruction of skeletal muscle mitochondria is considered as a promising adjunctive therapy in Duchenne muscular dystrophy (DMD). In this work, we study the effect of intraperitoneal administration of a non-immunosuppressive inhibitor of calcium-dependent mitochondria...

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Detalles Bibliográficos
Autores principales: Dubinin, Mikhail V., Starinets, Vlada S., Talanov, Eugeny Yu., Mikheeva, Irina B., Belosludtseva, Natalia V., Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464657/
https://www.ncbi.nlm.nih.gov/pubmed/34575944
http://dx.doi.org/10.3390/ijms22189780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464657/
https://www.ncbi.nlm.nih.gov/pubmed/34575944
http://dx.doi.org/10.3390/ijms22189780

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