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Porcine Circovirus (PCV) Genotype 2d-Based Virus-like Particles (VLPs) Induced Broad Cross-Neutralizing Antibodies against Diverse Genotypes and Provided Protection in Dual-Challenge Infection of a PCV2d Virus and a Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

As PCV2d infection has been continuously reported in swine farms in which pigs were vaccinated with PCV2a- or 2d-based vaccines, we attempted to develop a novel vaccine using a PCV2d-based capsid to enhance its protective efficacy. In this study, recombinant virus-like particles (VLPs) of rPCV2a, rP...

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Detalles Bibliográficos
Autores principales: Kang, Seok-Jin, Bae, Sung-Min, Lee, Hye-Jeong, Jeong, Young-Ju, Lee, Min-A, You, Su-Hwa, Lee, Hyang-Sim, Hyun, Bang-Hun, Lee, Nakhyung, Cha, Sang-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464671/
https://www.ncbi.nlm.nih.gov/pubmed/34578177
http://dx.doi.org/10.3390/pathogens10091145