Clotrimazole Fluidizes Phospholipid Membranes and Localizes at the Hydrophobic Part near the Polar Part of the Membrane

Clotrimazole (1-[(2-chlorophenyl)-diphenylmethyl]-imidazole) is an azole antifungal drug belonging to the imidazole subclass that is widely used in pharmacology and that can be incorporated in membranes. We studied its interaction with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) phospholipid...

Descripción completa

Detalles Bibliográficos
Autores principales: Ausili, Alessio, Yakymenko, Illya, Teruel, José A., Gómez-Fernández, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464689/
https://www.ncbi.nlm.nih.gov/pubmed/34572517
http://dx.doi.org/10.3390/biom11091304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464689/
https://www.ncbi.nlm.nih.gov/pubmed/34572517
http://dx.doi.org/10.3390/biom11091304

Ejemplares similares