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Bioconjugation Strategies for Connecting Proteins to DNA-Linkers for Single-Molecule Force-Based Experiments

The mechanical properties of proteins can be studied with single molecule force spectroscopy (SMFS) using optical tweezers, atomic force microscopy and magnetic tweezers. It is common to utilize a flexible linker between the protein and trapped probe to exclude short-range interactions in SMFS exper...

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Detalles Bibliográficos
Autores principales: van der Sleen, Lyan M., Tych, Katarzyna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464727/
https://www.ncbi.nlm.nih.gov/pubmed/34578744
http://dx.doi.org/10.3390/nano11092424