Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics

Precision dosing of piperacillin/tazobactam in obese patients is compromised by sparse information on target-site exposure. We aimed to evaluate the appropriateness of current and alternative piperacillin/tazobactam dosages in obese and nonobese patients. Based on a prospective, controlled clinical...

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Detalles Bibliográficos
Autores principales: Busse, David, Simon, Philipp, Petroff, David, Dorn, Christoph, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464843/
https://www.ncbi.nlm.nih.gov/pubmed/34575456
http://dx.doi.org/10.3390/pharmaceutics13091380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464843/
https://www.ncbi.nlm.nih.gov/pubmed/34575456
http://dx.doi.org/10.3390/pharmaceutics13091380

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