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TNF-α Increases IP-10 Expression in MCF-7 Breast Cancer Cells via Activation of the JNK/c-Jun Pathways

IP-10 (also called CXCL10) plays a significant role in leukocyte homing to inflamed tissues, and increased IP-10 levels are associated with the pathologies of various inflammatory disorders, including type 2 diabetes, atherosclerosis, and cancer. TNF-α is a potent activator of immune cells and induc...

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Detalles Bibliográficos
Autores principales: Kochumon, Shihab, Al-Sayyar, Amnah, Jacob, Texy, Hasan, Amal, Al-Mulla, Fahd, Sindhu, Sardar, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464892/
https://www.ncbi.nlm.nih.gov/pubmed/34572567
http://dx.doi.org/10.3390/biom11091355