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Epicatechin Gallate as Xanthine Oxidase Inhibitor: Inhibitory Kinetics, Binding Characteristics, Synergistic Inhibition, and Action Mechanism

Epicatechin gallate (ECG) is one of the main components of catechins and has multiple bioactivities. In this work, the inhibitory ability and molecular mechanism of ECG on XO were investigated systematically. ECG was determined as a mixed xanthine oxidase (XO) inhibitor with an IC(50) value of 19.33...

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Detalles Bibliográficos
Autores principales: Zhu, Miao, Pan, Junhui, Hu, Xing, Zhang, Guowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464939/
https://www.ncbi.nlm.nih.gov/pubmed/34574301
http://dx.doi.org/10.3390/foods10092191