Targeted Downregulation of MYC through G-quadruplex Stabilization by DNAi

Modulating the expression or function of the enigmatic MYC protein has demonstrated efficacy in an array of cancer types and a marked potential therapeutic index and safety profile. Despite its high therapeutic value, specific and selective inhibitors or downregulating therapeutics have proven diffi...

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Detalles Bibliográficos
Autores principales: Psaras, Alexandra Maria, Chang, Katarina T., Hao, Taisen, Brooks, Tracy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464964/
https://www.ncbi.nlm.nih.gov/pubmed/34577013
http://dx.doi.org/10.3390/molecules26185542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464964/
https://www.ncbi.nlm.nih.gov/pubmed/34577013
http://dx.doi.org/10.3390/molecules26185542

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