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Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells

Chronic inflammation induces autoimmune disorders and chronic diseases. Several natural products activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, attenuating inflammatory responses. Ergosta-7,9(11),22-trien-3β-ol (EK100) isolated from Cordyceps militaris showed anti-inflammator...

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Detalles Bibliográficos
Autores principales: Huang, Yi-Ping, Chen, Dar-Ren, Lin, Wen-Jen, Lin, Yu-Hsien, Chen, Jiann-Yeu, Kuo, Yueh-Hsiung, Chung, Jing-Gung, Hsia, Te-Chun, Hsieh, Wen-Tsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8464970/
https://www.ncbi.nlm.nih.gov/pubmed/34573062
http://dx.doi.org/10.3390/antiox10091430