Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma

SIMPLE SUMMARY: This review explores the current trials using cellular immunotherapies in pediatric sarcoma and describes examples of promising new CAR T targets in sarcoma that are in preclinical development. We provide insights into the ways in which the immunosuppressive tumor immune microenviron...

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Detalles Bibliográficos
Autores principales: Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J., Ekert, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465026/
https://www.ncbi.nlm.nih.gov/pubmed/34572932
http://dx.doi.org/10.3390/cancers13184704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465026/
https://www.ncbi.nlm.nih.gov/pubmed/34572932
http://dx.doi.org/10.3390/cancers13184704

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