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Cell Models for Chromosome 20q11.21 Amplification and Drug Sensitivities in Colorectal Cancer

Background and objectives: The chromosome locus 20q11.21 is a commonly amplified locus in colorectal cancer, with a prevalence of 8% to 9%. Several candidate cancer-associated genes are transcribed from the locus. The therapeutic implications of the amplification in colorectal cancer remain unclear....

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Detalles Bibliográficos
Autor principal: Voutsadakis, Ioannis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465100/
https://www.ncbi.nlm.nih.gov/pubmed/34577783
http://dx.doi.org/10.3390/medicina57090860