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Functional Analysis of p21(Cip1/CDKN1A) and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes. The cell cycle regulator p21(Cip1/CDKN1A) (p21) and its family members p27 and p57 regulate signaling pathways fundamental to placental development. Th...

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Detalles Bibliográficos
Autores principales: Kreis, Nina-Naomi, Friemel, Alexandra, Jennewein, Lukas, Hoock, Samira Catharina, Hentrich, Anna Elisabeth, Nowak, Thorsten, Louwen, Frank, Yuan, Juping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465116/
https://www.ncbi.nlm.nih.gov/pubmed/34571867
http://dx.doi.org/10.3390/cells10092214