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Expression of p53 Protein Associates with Anti-PD-L1 Treatment Response on Human-Derived Xenograft Model of GATA3/CR5/6-Negative Recurrent Nonmuscular Invasive Bladder Urothelial Carcinoma

Background: The possible involvement of p53 signaling, FGFR3 expression, and FGFR3 mutation rates in the prediction of the NMIBC anti-PD-L1 treatment response needs to be clarified. The main aim of our study was to explore predictive value of p53 expression, FGFR3 expression, and its gene mutation s...

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Detalles Bibliográficos
Autores principales: Blinova, Ekaterina, Samishina, Elena, Deryabina, Olga, Blinov, Dmitry, Roshchin, Dmitry, Shich, Evgeniia, Tumutolova, Oxana, Fedoseykin, Ilya, Epishkina, Anna, Barakat, Haydar, Kaprin, Andrey, Zhandarov, Kirill, Perepechin, Dmitrij, Merinov, Dmitrij, Brykin, Gordey, Arutiunian, Karen, Serebrianyi, Stanislav, Mirontsev, Artem, Kozdoba, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465184/
https://www.ncbi.nlm.nih.gov/pubmed/34576020
http://dx.doi.org/10.3390/ijms22189856