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Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells

We aimed to investigate the effect of acute glucose shift on the activation of the NLRP3 inflammasome, IL-1β secretion, and underlying signaling pathways in THP-1 cells. THP-1 cells were divided into four groups and exposed to the following glucose concentrations for 24 h: constant normal glucose (N...

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Detalles Bibliográficos
Autores principales: Lee, Ji Yeon, Kang, Yup, Kim, Hae Jin, Kim, Dae Jung, Lee, Kwan Woo, Han, Seung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465199/
https://www.ncbi.nlm.nih.gov/pubmed/34576117
http://dx.doi.org/10.3390/ijms22189952