Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons

Autophagic/lysosomal dysfunction is a critical pathogenesis of neuronal injury after ischemic stroke. Trehalose has been validated to restore the impaired autophagy flux by boosting transcription factor EB (TFEB) nuclear translocation, but orally administrated trehalose can be greatly digested by in...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zhiyuan, Zhang, Yongjie, Liu, Yuyuan, Chen, Xuemei, Huang, Zhiwen, Zhao, Xiaoming, He, Hongyun, Deng, Yihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465207/
https://www.ncbi.nlm.nih.gov/pubmed/34575099
http://dx.doi.org/10.3390/life11090948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465207/
https://www.ncbi.nlm.nih.gov/pubmed/34575099
http://dx.doi.org/10.3390/life11090948

Ejemplares similares