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A Physiologically Based Pharmacokinetic Model for Predicting Diazepam Pharmacokinetics after Intravenous, Oral, Intranasal, and Rectal Applications

Diazepam is one of the most prescribed anxiolytic and anticonvulsant that is administered through intravenous (IV), oral, intramuscular, intranasal, and rectal routes. To facilitate the clinical use of diazepam, there is a need to develop formulations that are convenient to administer in ambulatory...

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Detalles Bibliográficos
Autores principales: Khalid, Sundus, Rasool, Muhammad Fawad, Imran, Imran, Majeed, Abdul, Saeed, Hamid, Rehman, Anees ur, Ashraf, Waseem, Ahmad, Tanveer, Bin Jardan, Yousef A., Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465253/
https://www.ncbi.nlm.nih.gov/pubmed/34575556
http://dx.doi.org/10.3390/pharmaceutics13091480