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p53 mRNA Metabolism Links with the DNA Damage Response

Human cells are subjected to continuous challenges by different genotoxic stress attacks. DNA damage leads to erroneous mutations, which can alter the function of oncogenes or tumor suppressors, resulting in cancer development. To circumvent this, cells activate the DNA damage response (DDR), which...

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Detalles Bibliográficos
Autores principales: Vadivel Gnanasundram, Sivakumar, Bonczek, Ondrej, Wang, Lixiao, Chen, Sa, Fahraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465283/
https://www.ncbi.nlm.nih.gov/pubmed/34573428
http://dx.doi.org/10.3390/genes12091446