Asymmetric Total Syntheses of Both Enantiomers of Plymuthipyranone B and Its Unnatural Analogues: Evaluation of anti-MRSA Activity and Its Chiral Discrimination

Chiral total syntheses of both enantiomers of the anti-MRSA active plymuthipyranone B and all of the both enantiomers of three unnatural and synthetic analogues were performed. These two pairs of four chiral compounds are composed of the same 3-acyl-5,6-dihydro-2H-pyran-2-one structure. The starting...

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Detalles Bibliográficos
Autores principales: Moriyama, Mizuki, Liu, Xiaoxi, Enoki, Yuki, Matsumoto, Kazuaki, Tanabe, Yoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465287/
https://www.ncbi.nlm.nih.gov/pubmed/34577639
http://dx.doi.org/10.3390/ph14090938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465287/
https://www.ncbi.nlm.nih.gov/pubmed/34577639
http://dx.doi.org/10.3390/ph14090938

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