Zoledronic Acid as a Novel Dual Blocker of KIR6.1/2-SUR2 Subunits of ATP-Sensitive K(+) Channels: Role in the Adverse Drug Reactions

Zoledronic acid (ZOL) is used as a bone-specific antiresorptive drug with antimyeloma effects. Adverse drug reactions (A.D.R.) are associated with ZOL-therapy, whose mechanics are unknown. ZOL is a nitrogen-containing molecule whose structure shows similarities with nucleotides, ligands of ATP-sensi...

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Detalles Bibliográficos
Autores principales: Maqoud, Fatima, Scala, Rosa, Tragni, Vincenzo, Pierri, Ciro Leonardo, Perrone, Maria Grazia, Scilimati, Antonio, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465290/
https://www.ncbi.nlm.nih.gov/pubmed/34575427
http://dx.doi.org/10.3390/pharmaceutics13091350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465290/
https://www.ncbi.nlm.nih.gov/pubmed/34575427
http://dx.doi.org/10.3390/pharmaceutics13091350

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