Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds

Inhibiting the main protease 3CLpro is the most common strategy in the search for antiviral drugs to fight the infection from SARS-CoV-2. We report that the natural compound eugenol is able to hamper in vitro the enzymatic activity of 3CLpro, the SARS-CoV-2 main protease, with an inhibition constant...

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Detalles Bibliográficos
Autores principales: Rizzuti, Bruno, Ceballos-Laita, Laura, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Vega, Sonia, Grande, Fedora, Conforti, Filomena, Abian, Olga, Velazquez-Campoy, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465303/
https://www.ncbi.nlm.nih.gov/pubmed/34577592
http://dx.doi.org/10.3390/ph14090892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465303/
https://www.ncbi.nlm.nih.gov/pubmed/34577592
http://dx.doi.org/10.3390/ph14090892

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