Induced Pluripotent Stem Cells to Model Juvenile Myelomonocytic Leukemia: New Perspectives for Preclinical Research

Juvenile myelomonocytic leukemia (JMML) is a malignant myeloproliferative disorder arising in infants and young children. The origin of this neoplasm is attributed to an early deregulation of the Ras signaling pathway in multipotent hematopoietic stem/progenitor cells. Since JMML is notoriously refr...

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Detalles Bibliográficos
Autores principales: Wehbe, Zeinab, Ghanjati, Foued, Flotho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465353/
https://www.ncbi.nlm.nih.gov/pubmed/34571984
http://dx.doi.org/10.3390/cells10092335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465353/
https://www.ncbi.nlm.nih.gov/pubmed/34571984
http://dx.doi.org/10.3390/cells10092335

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