Biomimetic Ketone Reduction by Disulfide Radical Anion

The conversion of ribonucleosides to 2′-deoxyribonucleosides is catalyzed by ribonucleoside reductase enzymes in nature. One of the key steps in this complex radical mechanism is the reduction of the 3′-ketodeoxynucleotide by a pair of cysteine residues, providing the electrons via a disulfide radic...

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Detalles Bibliográficos
Autores principales: Barata-Vallejo, Sebastian, Skotnicki, Konrad, Ferreri, Carla, Marciniak, Bronislaw, Bobrowski, Krzysztof, Chatgilialoglu, Chryssostomos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465479/
https://www.ncbi.nlm.nih.gov/pubmed/34576900
http://dx.doi.org/10.3390/molecules26185429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465479/
https://www.ncbi.nlm.nih.gov/pubmed/34576900
http://dx.doi.org/10.3390/molecules26185429

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