High Mutational Heterogeneity, and New Mutations in the Human Coagulation Factor V Gene. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies

Factor V is an essential clotting factor that plays a key role in the blood coagulation cascade on account of its procoagulant and anticoagulant activity. Eighty percent of circulating factor V is produced in the liver and the remaining 20% originates in the α-granules of platelets. In humans, the f...

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Detalles Bibliográficos
Autores principales: Bernal, Sara, Pelaez, Irene, Alias, Laura, Baena, Manel, De Pablo-Moreno, Juan A., Serrano, Luis J., Camero, M. Dolores, Tizzano, Eduardo F., Berrueco, Ruben, Liras, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465496/
https://www.ncbi.nlm.nih.gov/pubmed/34575869
http://dx.doi.org/10.3390/ijms22189705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465496/
https://www.ncbi.nlm.nih.gov/pubmed/34575869
http://dx.doi.org/10.3390/ijms22189705

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